Related Experiment Video
Updated: Jun 15, 2026

A Method to Test the Efficacy of Handwashing for the Removal of Emerging Infectious Pathogens
Published on: June 7, 2017
The hygiene hypothesis: an evolutionary perspective
Manuela Sironi1, Mario Clerici
1Scientific Institute IRCCS E. Medea, Bioinformatics, Via don L. Monza 20, 23842 Bosisio Parini (LC), Italy. manuela.sironi@bp.lnf.it
Abstract:
The hygiene hypothesis relies on the assumption that humans have adapted to a pathogen-rich environment that no longer exists in industrialized societies. Recent advances in molecular immunology and population genetics allow deeper insight into the evolution and co-evolution of host-pathogen interactions and, therefore, into the foundations of the hygiene hypothesis.
Related Concept Videos
Criticisms of the Evolutionary Perspective
Evolutionary psychology provides one explanation for these findings, suggesting...
Microbiota of the Urogenital Tract
Development of the Oral Microbiota
Evolutionary Psychology
The Oral Microbiota
Evolution of New Traits in Microbes

