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Related Experiment Video

Updated: Jun 15, 2026

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

Published on: October 12, 2018

HIV infection and women's sexual functioning.

Tracey E Wilson¹, Girardin Jean-Louis, Rebecca Schwartz

¹Department of Community Health Sciences, State University of New York, Downstate Medical Center, Brooklyn, NY 11203, USA. tracey.wilson@downstate.edu

Journal of Acquired Immune Deficiency Syndromes (1999)

|February 25, 2010

Summary

This summary is machine-generated.

Women with HIV experience more sexual problems than HIV-negative women. Factors like menopause, depression, relationship status, and lower CD4 counts impact sexual function in women living with HIV.

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Collection, Isolation, and Flow Cytometric Analysis of Human Endocervical Samples

Collection, Isolation, and Flow Cytometric Analysis of Human Endocervical Samples

Published on: July 6, 2014

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Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture

Published on: October 12, 2018

Collection, Isolation, and Flow Cytometric Analysis of Human Endocervical Samples

Collection, Isolation, and Flow Cytometric Analysis of Human Endocervical Samples

Published on: July 6, 2014

Area of Science:

Women's Health Research
Infectious Disease Epidemiology
Sexual Health Studies

Background:

The Women's Interagency HIV Study (WIHS) investigates the history of HIV in US women.
Understanding sexual health is crucial for women's overall well-being, especially those with HIV.

Purpose of the Study:

To compare sexual problems in HIV-positive versus HIV-negative women.
To identify clinical and psychosocial factors linked to sexual dysfunction in women.

Main Methods:

1805 women (1279 HIV+, 526 HIV-) completed study visits between Oct 2006-Mar 2007.
Data collection included the Female Sexual Function Index (FSFI), surveys, exams, and blood tests.
CD4 cell counts were analyzed in relation to sexual function scores.

Main Results:

HIV-positive women reported significantly more sexual problems than HIV-negative women.
Menopausal status, depressive symptoms, and lack of a relationship were associated with lower sexual function.
Lower CD4 cell counts (≤199 cells/µL) correlated with poorer sexual functioning.

Conclusions:

Sexual problems are more prevalent in women with HIV and are influenced by various factors.
Addressing sexual health is essential for comprehensive HIV care and improving quality of life.
Further research and clinical attention are needed to integrate sexual health into routine HIV management.