CT of AIDS-related lymphoma

A spectrum of CT findings in patients with AIDS-related lymphoma (ARL) is illustrated herein. When a solid mass anywhere in the body is encountered in a patient with AIDS, lymphoma must be considered in the differential diagnosis. Although the CT findings alone generally are not enough for a specific diagnosis of lymphoma, this frequently will be suggested as the most likely diagnosis, facilitating further workup. CT-guided biopsy is useful in providing tissue diagnosis in many cases.