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Updated: Jun 15, 2026

Zebrafish Model of Neuroblastoma Metastasis
Published on: March 14, 2021
Unusual fatty metamorphosis observed in diffuse liver metastases of stage 4S neuroblastoma
Jun Tazoe1, Chio Okuyama, Tomoko Iehara
1Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajiicho Kawaramachi Hirokoji Kamigyo-ku, Kyoto City, 602-8566, Japan. juntazoe@gmail.com
Abstract:
We report a case of stage 4S neuroblastoma in which CT showed diffuse liver metastases containing a geographical fatty area in the periportal region. MRI showed this abnormality to correspond to an area with an unusual pattern of fatty change. (123)I-metaiodobenzylguanidine (MIBG) scintigraphy demonstrated increased accumulation throughout the liver, except for the region showing fatty change. To the best of our knowledge, this is the first report of liver metastases from neuroblastoma with geographical fatty infiltration.
