Related Experiment Video
Updated: Jun 15, 2026

Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury
Published on: July 17, 2016
Acute postrenal azotemia: etiology, clinicopathology, and pathophysiology
Julia Fischer1, India Lane, Jennifer Stokes
1Veterinary Specialty Hospital-San Diego, CA, USA.
Abstract:
When rupture or obstruction of the urinary tract prevents the normal collection and expulsion of urine from the body, the resulting azotemia is termed postrenal. Postrenal azotemia can coexist with prerenal and/or renal azotemia. Detection of postrenal azotemia requires attentiveness to the history and physical examination findings and to the results of specifically directed diagnostic tests. Prompt correction of postrenal causes of azotemia limits the potential for intrinsic renal damage and can contribute to a positive clinical outcome; therefore, postrenal azotemia should be investigated in all azotemic patients.
Related Concept Videos
Acute Kidney Injury II: Pathophysiology
Acute Kidney Injury III: Clinical Manifestations
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Acute Pyelonephritis I: Introduction
Acute Kidney Injury I: Introduction
Acute Kidney Injury V: Interprofessional Care