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Published on: November 21, 2013
Methods of recruiting adolescents with psychiatric and substance use disorders for a clinical trial
William B Jaffee1, Genie L Bailey, Michelle Lohman
1Mclean Hospital, Harvard Medical School, Massachusetts, USA.
Background:
The present article reports on recruiting strategies in a 16-week, multi-site trial of osmotic-release methylphenidate combined with cognitive-behavioral therapy in adolescents with co-occurring attention deficit hyperactivity disorder and substance use disorder.
Methods:
A multifaceted recruiting strategy was employed that targeted multiple referral sources, used incentives, involved numerous staff members, emphasized the therapeutic alliance during prescreening, and utilized data to modify strategies based on results. Overall, 303 adolescents were randomized from 1,333 total referrals across 11 participating sites.
Results:
Overall, existing treatment program sources, including treatment program staff, social services, the juvenile justice system, and mental health clinics provided a majority of referrals for pre-screening and randomization.
Conclusions And Scientific Significance:
These results support the feasibility of recruiting dually-diagnosed adolescents utilizing a multifaceted approach involving the entire study team.
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