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Related Experiment Video

Updated: Jun 15, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Ungual seborrheic keratosis.

M Bon-Mardion¹, N Poulalhon, B Balme

¹Department of Dermatology, Centre Hospitalier Lyon Sud, Pierre Bénite Cedex, France.

Journal of the European Academy of Dermatology and Venereology : JEADV

|February 26, 2010

Summary

This summary is machine-generated.

This study reports the first documented case of a typical seborrheic keratosis on the nail bed. This benign skin tumor diagnosis in the nail bed warrants inclusion in the differential for longitudinal leukonychia.

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Area of Science:

Dermatology
Oncology
Pathology

Background:

Seborrheic keratoses are common benign epithelial skin tumors.
Unusual locations for seborrheic keratoses have been documented.
The nail bed is a rare site for these tumors.

Observation:

A 58-year-old male presented with a year-long history of longitudinal leukonychia on his right hallux.
The patient underwent surgical treatment for the nail abnormality.
Histological examination confirmed the presence of a typical seborrheic keratosis.

Findings:

This case represents the first histologically confirmed instance of a typical seborrheic keratosis originating from the nail bed.
The histological features were consistent with a standard seborrheic keratosis.

Implications:

Seborrheic keratosis of the nail bed should be considered in the differential diagnosis of acquired longitudinal leukonychia.
Surgical intervention is crucial for accurate diagnosis and to exclude other potential conditions, such as squamous cell carcinoma.
This finding expands the known anatomical distribution of seborrheic keratoses.