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Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus (KSHV)
Published on: September 14, 2010
Kaposi's sarcoma responding to topical imiquimod 5% cream: a case report
Sophia Benomar1, Saber Boutayeb, Leila Benzekri
1Department of Dermatology, Ibn Sina Hospital, Rabat, Morocco. Sophia.boutayeb@yahoo.fr
Abstract:
Kaposi's sarcoma, a virus-associated neoplasm, can be treated with systemic therapy such interferon or chemotherapy, although a local alternative is possible in localized disease.Topical imiquimod is a ligand of the toll-like receptors 7 and 8 on dendritic cells, increasing immune responses and showing antiviral and antitumoral activities. We report a spectacular response to imiquimod 5% cream in a patient with classic Kaposi's sarcoma of the leg.
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