Improving adherence to medication in stroke survivors (IAMSS): a randomised controlled trial: study protocol

Area of Science:

• Neurology
• Pharmacology
• Public Health

Background:

• Medication adherence is crucial for chronic disease management, yet suboptimal adherence affects 50% of patients globally.
• Previous research indicated 30% of stroke patients have poor adherence, linked to age, cognitive issues, and medication concerns.
• A significant gap exists in effective interventions for improving medication adherence post-stroke.

Purpose of the Study:

• To pilot a brief intervention designed to improve medication adherence in stroke patients.
• To help patients establish better medication-taking routines.
• To address and modify erroneous beliefs about medications and stroke.

Main Methods:

• A pilot study involving 60 stroke patients, with 30 receiving a brief intervention and 30 receiving usual care.
• Medication adherence measured over 3 months using Medication Event Monitoring System (MEMS) devices.
• Secondary outcomes include self-reported adherence and blood pressure monitoring.

Main Results:

• Data on adherence, feasibility, and patient acceptance of the intervention will be collected.
• The study will provide preliminary data on the intervention's potential effectiveness.
• Analysis will focus on uptake, attrition, and patient understanding.

Conclusions:

• This pilot study will assess the feasibility and acceptability of a novel intervention for stroke patients.
• Findings will inform the design of larger trials to improve medication adherence and patient outcomes.
• The intervention shows promise for enhancing routine-based adherence and addressing cognitive barriers.