Related Experiment Video
Updated: Jun 15, 2026

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound (30/45MHZ) System
Published on: May 5, 2018
Congenital heart disease and multi-modality imaging
Rajesh Puranik1, Vivek Muthurangu, David S Celermajer
1Cardiovascular Magnetic Resonance Unit, Great Ormond St Hospital, UK. rpuranik@mail.usyd.edu.au <rpuranik@mail.usyd.edu.au>
Insights
Advances in cardiovascular magnetic resonance (MR) and computed tomography (CT) offer non-invasive imaging for adult congenital heart disease (CHD). These techniques provide detailed anatomical and functional assessments, improving patient management.
Area of Science:
- Cardiology
- Medical Imaging
- Radiology
Background:
- Adult congenital heart disease (CHD) prevalence is rising due to improved pediatric care.
- Echocardiography is standard, but advanced imaging offers new diagnostic capabilities.
Purpose of the Study:
- To review the role of cardiovascular magnetic resonance (MR) and computed tomography (CT) in managing adult congenital heart disease (CHD).
- To detail recent developments in imaging techniques for common CHD diagnoses.
Main Methods:
- Review of cardiovascular MR techniques (spin-echo, gradient-echo, phase-contrast, gadolinium-enhanced MR angiography).
- Review of multi-detector CT capabilities for rapid, multi-planar, and 3D image reconstruction.
- Comparison with traditional invasive X-ray angiography.
Main Results:
- Cardiovascular MR allows comprehensive assessment of cardiac anatomy, function, sequelae, and complications.
- CT enables rapid data acquisition and multi-planar/3D reconstructions.
- Non-invasive MR and CT are desirable alternatives to invasive angiography for CHD patients.
Conclusions:
- Advanced imaging modalities like cardiovascular MR and CT are crucial for the diagnosis and management of adult CHD.
- These non-invasive techniques provide detailed insights into cardiac structure and function, aiding in the assessment of surgical outcomes and complications.
Abstract:
The increasing prevalence of adult congenital heart disease (CHD) can be attributed to major improvements in diagnosis and treatment of children with CHD. Although, echocardiography is the most commonly used imaging modality for diagnosis and follow up of subjects with CHD, the evolution of both cardiovascular magnetic resonance (MR) imaging and computed tomography (CT) does offer new ways to visualise the heart and great vessels. Cardiovascular MR techniques such as spin-echo and gradient-echo imaging, velocity-encoded phase-contrast MR and gadolinium-enhanced MR angiography allow comprehensive assessment of cardiac anatomy and function. This provides information about the long-term sequelae of the underlying anatomy, haemodynamic assessment of residual post-operative lesions and complications of surgery. Similarly, the development of spiral and subsequently multi-detector CT enables the acquisition of data during a single breath-hold and during the first pass of a contrast bolus, so that images can be reconstructed in any two-dimensional plane or in three-dimensions. As much of the functional data in CHD patients was traditionally acquired with invasive X-ray angiography, non-invasive alternatives such as cardiovascular MR and CT are desirable. This review evaluates the role of imaging modalities in the management of subjects with CHD, particularly detailing recent developments in imaging techniques as they relate to the various CHD diagnoses commonly encountered in practice.
Related Concept Videos
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Mitral Stenosis II: Clinical features and Diagnostic Tests

