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Updated: Jun 15, 2026
10:46
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Management of acute exacerbations in multiple sclerosis
Daniel Ontaneda1, Alex D Rae-Grant
1Neurological Institute, Cleveland Clinic, Cleveland, Ohio, 44195 USA.
Annals of Indian Academy of Neurology
|February 26, 2010
Summary
Multiple sclerosis exacerbations involve new or worsening symptoms over weeks. This review covers their causes, treatments, and integration into overall multiple sclerosis management.
Area of Science:
- Neurology
- Immunology
Background:
- Multiple sclerosis (MS) is a chronic neurological disease.
- MS exacerbations are characterized by new or worsening neurological symptoms over days to weeks.
Purpose of the Study:
- To review the pathophysiology of multiple sclerosis exacerbations.
- To summarize current and emerging treatments for MS exacerbations.
- To discuss the role of exacerbations in the comprehensive management of multiple sclerosis.
Main Methods:
- Literature review of pathophysiology and treatment of MS exacerbations.
- Analysis of current clinical guidelines and research studies.
- Synthesis of information for a holistic management approach.
Main Results:
- Exacerbations result from inflammatory demyelination in the central nervous system.
- Treatment options include corticosteroids and disease-modifying therapies.
- Effective management requires timely diagnosis and tailored therapeutic strategies.
Conclusions:
- Understanding MS exacerbation pathophysiology is crucial for effective treatment.
- A multi-faceted approach integrating acute management and long-term disease control is essential.
- Optimizing MS care involves addressing exacerbations within the broader disease context.
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