Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Drug Dependence01:17

Drug Dependence

Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Stimulants01:29

Stimulants

Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
Drug Toxicity: Overview01:00

Drug Toxicity: Overview

Drug toxicity quantifies the harm a compound causes to an organism, varying by dose and potentially impacting whole systems or specific organs like the liver. Toxic reactions may arise from venomous insect or spider bites, with effects ranging from mild symptoms to severe outcomes such as brain damage or death. Common forms of acute poisoning include ethanol intoxication and overdose of pain or fever medications, with substances like GHB and heroin being particularly lethal at doses close to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dialectical behavior therapy (DBT) in an assertive community treatment structure (ACT): testing integrated care borderline (ICB) in a randomized controlled trial (RECOVER).

Borderline personality disorder and emotion dysregulation·2024
Same author

Is loneliness associated with cancellation of medical appointments during the COVID-19 pandemic? Evidence from the Hamburg City Health Study (HCHS).

BMC health services research·2024
Same author

Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profile.

Purinergic signalling·2021
Same author

Childhood maltreatment and treatment outcome in psychotic disorders: a systematic review and meta-analysis.

Acta psychiatrica Scandinavica·2019
Same author

Atopic dermatitis shows significant cutaneous comorbidity: results from large-scale investigations in the working population.

Journal of the European Academy of Dermatology and Venereology : JEADV·2019
Same author

[Social rights claims for malignant melanoma patients : Providing patient information in German dermatological practices].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2019
Same journal

[Applying the German demand planning guideline to maternity care provision: regional and socioeconomic disparities].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·2026
Same journal

[Medical aids for children and adolescents following the legislative change-a status report].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·2026
Same journal

[Doping: caught between fraud, health protection, and responsibility].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·2026
Same journal

[Aging with intellectual and developmental disabilities or severe multiple disabilities-health, participation, and care in later life].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·2026
Same journal

[Sexual self-determination and disability: 10 years of the ReWiKs project-dynamics and findings].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·2026
Same journal

[Legal and societal aspects of doping in sport].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·2026
See all related articles

Related Experiment Video

Updated: Jun 15, 2026

Comprehensive Analysis of Transcription Dynamics from Brain Samples Following Behavioral Experience
08:14

Comprehensive Analysis of Transcription Dynamics from Brain Samples Following Behavioral Experience

Published on: August 26, 2014

[What do we mean by addiction?].

C Haasen1, A Kutzer, I Schäfer

  • 1Klinik für Psychiatrie und Psychotherapie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland. haasen@uke.de

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
|February 26, 2010
PubMed
Summary
This summary is machine-generated.

Addiction research is evolving beyond substance use disorders to include behavioral addictions. Future diagnostic systems will likely group these together due to neurobiological similarities.

More Related Videos

A Conflict Model of Reward-seeking Behavior in Male Rats
06:11

A Conflict Model of Reward-seeking Behavior in Male Rats

Published on: February 20, 2019

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community
08:53

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community

Published on: May 31, 2019

Related Experiment Videos

Last Updated: Jun 15, 2026

Comprehensive Analysis of Transcription Dynamics from Brain Samples Following Behavioral Experience
08:14

Comprehensive Analysis of Transcription Dynamics from Brain Samples Following Behavioral Experience

Published on: August 26, 2014

A Conflict Model of Reward-seeking Behavior in Male Rats
06:11

A Conflict Model of Reward-seeking Behavior in Male Rats

Published on: February 20, 2019

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community
08:53

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community

Published on: May 31, 2019

Area of Science:

  • Psychiatry and Behavioral Science
  • Neuroscience
  • Addiction Medicine

Context:

  • Historically, addiction disorders primarily encompassed substance use disorders, with a focus on dependence.
  • Current diagnostic systems (ICD and DSM) show high concordance for dependence criteria but less for harmful use/abuse.
  • Behavioral addiction diagnostic criteria are limited, with pathological gambling classified under impulse control disorders.

Purpose:

  • To analyze the evolution of addiction disorder classification.
  • To highlight the diagnostic discrepancies between substance use and behavioral addictions.
  • To discuss the implications of neurobiological evidence on future classification revisions.

Summary:

  • Addiction disorders were historically viewed as solely substance use disorders, focusing on dependence.
  • Diagnostic criteria for harmful use (ICD) and abuse (DSM) exhibit limited concordance.
  • Future revisions of the International Classification of Diseases (ICD) and Diagnostic and Statistical Manual of Mental Disorders (DSM) are expected to integrate behavioral addiction and substance use disorders.

Impact:

  • This shift will improve diagnostic accuracy and treatment for a broader range of addictive behaviors.
  • Recognizing neurobiological links will foster more integrated research and clinical approaches.
  • Enhanced classification will facilitate better understanding and management of addiction spectrum disorders.