[Rising PSA level and negative prostate biopsy. Can prostate elastography help?]

Previous studies investigated the clinical impact of elastography for preoperative staging and as an additional imaging modality to improve prostate cancer detection during prostate biopsy. This rapidly improving technique has facilitated progress toward feasibility and reproducibility of transrectal elastography. Recent studies show significant improvements using the latest generation of elastographic devices. Further studies are needed to evaluate on the one hand elastography-guided prostate biopsy schemes and results of saturation biopsies and on the other hand to compare sensitivity and specificity of elastographic detection of prostate cancer with different imaging techniques, especially magnetic resonance imaging and spectroscopy.