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Related Experiment Video

Updated: Jun 15, 2026

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice

Published on: May 16, 2019

Face to face with Phineas Gage.

Jack Wilgus¹, Beverly Wilgus

¹Photographers and Photographic Collectors, Maryland, USA. phineasgage@brightbytes.com

Journal of the History of the Neurosciences

|February 26, 2010

Summary

A rare daguerreotype, believed to be the only known image of Phineas Gage, has been reproduced. This image was compared to the Phineas Gage life mask and tamping iron.

Area of Science:

Neuroscience
Medical History
Forensic Imaging

Background:

A previously unknown daguerreotype, potentially the sole existing photograph of Phineas Gage, was acquired over 30 years ago.
The daguerreotype's subject was identified through rigorous comparative analysis.

Discussion:

The process of creating daguerreotypes is detailed, providing historical context for early photographic techniques.
The presented daguerreotype was meticulously compared against the Phineas Gage life mask and the tamping iron artifact.

Key Insights:

This study confirms the authenticity and significance of the daguerreotype as a unique visual record of Phineas Gage.
The comparative analysis strengthens the historical and scientific understanding of Phineas Gage's case.

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Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex

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Published on: April 15, 2015

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Last Updated: Jun 15, 2026

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice

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Published on: May 16, 2019

Long-term Potentiation of Perforant Pathway-dentate Gyrus Synapse in Freely Behaving Mice

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Published on: November 29, 2013

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex

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Published on: April 15, 2015

Outlook:

Further research may involve advanced imaging techniques to reveal finer details within the daguerreotype.
This finding offers new avenues for exploring historical medical cases through photographic evidence.