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Updated: Jun 15, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
[Endemic intravenous fluid contamination in pediatric wards]
Juan Manuel Muñoz1, Reynaldo Zapién, Samuel Ponce-De-León
1Facultad de Medicina, Universidad de Guanajuato, León. jmunozb@me.com
Objective:
To determine the rate of contamination of intravenous solutions and injection ports in pediatric patients.
Material And Methods:
During non-epidemic periods, eight pediatric wards in Mexican hospitals were studied. Qualitative cultures were performed from the surface of injection ports and from intravenous solutions in use in pediatric patients younger than 2 years, culturing 750 infusion systems from 728 patients.
Results:
The rate of contamination of intravenous solutions was 2.4% (18/750; CI 95%: 1.3% to 3.5%) and for injection ports it was 3.2% (24/750; CI 95%: 2.1% to 4.3%). Enterobacteriaceae predominated; in four cases the organisms isolated from the port and from the solutions were coincident (Klebsiella spp. and Enterobacter sp.). The rate of contamination for solutions mixed in the wards was 5.1%, against 1.3% of those not mixed (chi2 = 9.19, p < 0.01).
Discussion:
Contamination of parenteral solutions is not a rare phenomenon and it could be related to inappropriate practices in the preparation of intravenous solutions and medications as well as the contamination of injection ports. In hospitals working with standards similar to those reported here, the monitoring of sterility of intravenous solutions could contribute to reduce the rate of nosocomial bacteremia.
Insights
Intravenous solutions and injection ports in pediatric patients show significant contamination rates, with Enterobacteriaceae being the most common. In-ward mixing of solutions increased contamination risk, highlighting the need for sterility monitoring to prevent hospital-acquired infections.
Area of Science:
- Microbiology
- Infectious Diseases
- Hospital Epidemiology
Context:
- Pediatric healthcare settings face risks of healthcare-associated infections.
- Intravenous (IV) administration is a common route for medication delivery in pediatric patients.
- Maintaining sterility of IV solutions and access ports is critical for patient safety.
Purpose:
- To quantify the prevalence of microbial contamination on IV solutions and injection ports in pediatric patients.
- To identify common microorganisms associated with IV system contamination.
- To explore factors influencing contamination rates, such as solution preparation methods.
Summary:
- A study in Mexican hospitals found contamination rates of 2.4% for IV solutions and 3.2% for injection ports in pediatric patients.
- Enterobacteriaceae were the predominant contaminants. Solutions mixed within wards showed a higher contamination rate (5.1%) compared to those not mixed (1.3%).
- Coincidental contamination of both solutions and ports was observed in some cases.
Impact:
- Findings indicate that parenteral solution contamination is a notable issue in pediatric care.
- Inappropriate preparation practices and port contamination may contribute to the observed rates.
- Regular monitoring of IV solution sterility is recommended to reduce nosocomial bacteremia in pediatric populations.
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