Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Paranasal sinus cancer.

G P Bridger1, M S Mendelsohn, M Baldwin

  • 1Head and Neck Unit, Prince of Wales Hospital, Randwick, New South Wales, Australia.

The Australian and New Zealand Journal of Surgery
|April 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rheumatoid pannus presenting as a large epidural mass in the subaxial cervical spine: A case report.

Neuro-Chirurgie·2021
Same author

Patient Portal Use Near the End-of-Life.

Journal of general internal medicine·2021
Same author

First Results from the DEAP-3600 Dark Matter Search with Argon at SNOLAB.

Physical review letters·2018
Same author

Management of locally advanced T3-4 glottic laryngeal carcinomas.

The Journal of laryngology and otology·2018
Same author

A Cervico-Laryngeal Cyst.

The Australian and New Zealand journal of surgery·2017
Same author

Discordant Observation of Brain Injury by MRI and Malignant Electroencephalography Patterns in Comatose Survivors of Cardiac Arrest following Therapeutic Hypothermia.

AJNR. American journal of neuroradiology·2016
Same journal

The Experimental Application of Microsurgical Techniques to Internal Mammary to Coronary Artery Anastomosis.

The Australian and New Zealand journal of surgery·2018
Same journal

The Use of Trimethoprim-Sulphamethoxazole in the Treatment of Complicated Urinary Tract Infection.

The Australian and New Zealand journal of surgery·2018
Same journal

The Bairnsdale Ulcer.

The Australian and New Zealand journal of surgery·2018
Same journal

Aorto-Caval Fistula: Successful Management of Two Cases.

The Australian and New Zealand journal of surgery·2018
Same journal

Subdural Empyema.

The Australian and New Zealand journal of surgery·2018
Same journal

Massive Ascites Due to Pancreatic Stones.

The Australian and New Zealand journal of surgery·2018
See all related articles

Radical surgery for paranasal sinus malignancies offers survival benefits, particularly for adenocarcinoma and squamous cell carcinoma. Orbital exenteration impacts survival rates, while free flap transfers aid reconstruction.

Area of Science:

  • Otolaryngology
  • Surgical Oncology
  • Head and Neck Cancer Research

Background:

  • Paranasal sinus malignancies are rare but aggressive tumors.
  • Radical surgery is a primary treatment modality, often combined with radiotherapy.

Purpose of the Study:

  • To review treatment outcomes and survival rates for patients with paranasal sinus malignancies.
  • To evaluate the impact of surgical extent and adjuvant therapies on patient survival.

Main Methods:

  • Retrospective review of 65 patients treated with radical surgery.
  • Analysis of tumor location, histology, and treatment modalities (surgery, radiotherapy).
  • Assessment of 5-year survival rates based on cancer type and surgical approach.

Main Results:

Related Experiment Videos

  • 58 of 65 tumors were epithelial cancers.
  • 5-year survival rates: 78% for adenocarcinoma, 70% for squamous cell cancer and esthesioneuroblastoma.
  • Melanoma patients had no 5-year disease-free survival.
  • 5-year survival was 50% with orbital exenteration vs. 70% when the eye was spared.
  • Free flap transfers were used for large defect reconstruction.

Conclusions:

  • Radical surgery combined with radiotherapy can achieve favorable outcomes for specific paranasal sinus malignancies.
  • Tumor histology and extent of surgery, including orbital involvement, significantly influence survival.
  • Advanced reconstructive techniques like free flaps are crucial for managing complex sino-orbital defects.