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Updated: Jun 15, 2026

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
Published on: November 19, 2012
Post-traumatic amnesia and its relationship to the functional outcome of people with severe traumatic brain injury
1Brain Injury Unit, Royal Rehabilitation Centre Sydney, Ryde, NSW, Australia. yvette.kosch@sswahs.nsw.gov.au
Objective:
To investigate the relationship between Post-Traumatic Amnesia (PTA) duration, length of stay and functional outcomes in Australian in-patients with severe traumatic brain injury (TBI).
Design:
Retrospective, descriptive study using prospectively collected data from the Uniform Data Set for Medical Rehabilitation (UDSMR).
Methods:
Prospective collection of Westmead PTA scores and analysis of database for admissions for primary TBI rehabilitation from 1993-2003. Functional Independence Measure (FIM) was used to measure functional outcome. Statistical analysis using SPSS Version 13.
Results:
Six hundred and thirty-eight consecutive admissions; 611 patients had PTA classified by ranges, 436 of whom had an exact number of PTA days. Mean age 37.6 years; more than 90% had a PTA duration greater than 1 week. Significant predictors of discharge FIM scores and total length of hospitalization were PTA duration, admission FIM scores and acute length of hospitalization.
Conclusions:
PTA duration correlates with length of hospitalization and discharge function. PTA duration affects recovery rate. Implications include use of PTA duration for prognosticating, discharge planning and funding systems.
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