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A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

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Reevaluating the dead donor rule.

¹The Bioethics Program, Mount Sinai School of Medicine, One Gustave Levy Place, Box 1108, New York, NY 10029, USA. mike9943@gmail.com

The Journal of Medicine and Philosophy

|February 27, 2010

Summary

This summary is machine-generated.

The dead donor rule requires organ donors to be dead before organ removal. This study argues for allowing organ donation from individuals with severe brain damage before death, challenging current ethical standards.

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Area of Science:

Medical Ethics
Transplantation Medicine
Neurology

Background:

The dead donor rule is a cornerstone of organ procurement for transplantation.
Current practice relies heavily on declaring death by neurological criteria.
Significant ethical and medical debate surrounds the dead donor rule and neurological criteria for death.

Purpose of the Study:

To critically evaluate the reliability and justification of declaring death by neurological criteria.
To re-examine the ethical principles underpinning the dead donor rule.
To propose an alternative ethical framework for organ donation.

Main Methods:

Philosophical analysis of ethical principles related to death and organ donation.
Review of medical literature on neurological criteria for death.
Argumentative critique of the dead donor rule.

Main Results:

Declaring death by neurological criteria is presented as unreliable and unjustified.
The ethical principles supporting the dead donor rule can be better upheld by abandoning it.
Allowing organ donation from individuals with severe, irreversible brain damage prior to death is advocated.

Conclusions:

The dead donor rule should be abandoned to better serve ethical principles.
Individuals with severe and irreversible brain damage, not yet declared dead, could serve as organ donors.
Organ removal, even if the proximate cause of death, can be ethically permissible under revised guidelines.