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Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Gamma knife radiosurgery for central neurocytomas
Shigeo Matsunaga1, Takashi Shuto, Jun Suenaga
1Department of Neurosurgery, Yokohama Rosai Hospital, Yokohama, Kanagawa. shigeo-m@mui.biglobe.ne.jp
Neurologia Medico-Chirurgica
|February 27, 2010
Summary
Gamma knife radiosurgery (GKS) offers a high tumor control rate for central neurocytomas. This study suggests GKS is a viable option for residual or recurrent tumors, especially when detected early.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Background:
- Central neurocytomas are rare tumors with unclear long-term outcomes after treatment.
- Gamma knife radiosurgery (GKS) is a minimally invasive treatment option for brain tumors.
Observation:
- This study retrospectively reviewed 7 patients with 8 central neurocytomas treated with GKS between 1997 and 2007.
- All patients had prior incomplete surgical resections.
- Tumors were treated with a marginal dose of 12-18 Gy, with a mean follow-up of 63.6 months.
Findings:
- A high tumor control rate of 7/8 was observed.
- Only one patient died due to tumor recurrence and intracranial hemorrhage 40 months post-GKS.
- No malignant transformation was noted, but risks like progression, hemorrhage, and dissemination exist.
Implications:
- GKS demonstrates efficacy in controlling central neurocytoma growth.
- The study recommends GKS for residual or recurrent central neurocytomas, particularly with early detection.
- While effective, careful monitoring is advised due to potential postoperative complications.
