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Updated: Jun 15, 2026
04:45
Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
Published on: May 10, 2021
Excisional biopsy with margin control for oral cancers.
Yu-Chien Wang1, Ku-Hao Fang, Shih-Ming Jung
1Department of Otolaryngology-Head & Neck Surgery, Chang Gung Memorial Hospital, Linkou, Taiwan.
Head & Neck
|February 27, 2010
Summary
Excisional biopsy effectively removes oral lesions for diagnosis and treatment. This procedure demonstrated high accuracy in identifying malignancies and ensuring negative surgical margins for oral cancer patients.
Area of Science:
- Oral pathology
- Surgical oncology
- Head and neck cancer
Background:
- Oral lesions often present diagnostic challenges.
- Accurate diagnosis is crucial for effective treatment planning.
Purpose of the Study:
- To evaluate the efficacy of excisional biopsy for oral lesions.
- To assess its role in the diagnosis and management of potentially malignant or controversial oral lesions.
Main Methods:
- Retrospective review of 52 cases with 56 oral lesions.
- Excisional biopsy with intraoperative frozen section analysis was performed.
- Data collected from January 2003 to June 2008.
Main Results:
- 28 of 56 lesions were diagnosed as malignant.
- High underdiagnosis rate (7/12) noted in controversial diagnoses.
- All malignant cases achieved negative surgical margins; no simultaneous neck metastasis detected.
Conclusions:
- Excisional biopsy with margin control is a valuable diagnostic and therapeutic tool for oral cancers.
- The procedure aids in definitive diagnosis and treatment planning for oral malignancies.
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