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Updated: Jun 15, 2026

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma
Published on: August 9, 2016
Neoadjuvant therapy of locally advanced gastric cancer
James J Mezhir1, Laura H Tang, Daniel G Coit
1Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA. mezhirj@mskcc.org
Abstract:
Treatment of gastric cancer has evolved with the advent of randomized trials demonstrating chemotherapeutic agents with efficacy in advanced disease. Level I evidence supports delivering chemotherapy in the neoadjuvant setting; the data shows improvement in progression-free and overall survival. A clinical response to therapy is associated with improved R0 resection rates, pathologic response, and outcome in patients with locally advanced disease. Early assessment of metabolic response to therapy can potentially be utilized to tailor treatment.
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