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Published on: May 26, 2023
A patient with Lemierre syndrome.
Efthimia G Vargiami1, E Farmaki, D Tasiopoulou
11st Pediatric Clinic, Aristotle University of Thessaloniki, Dorilaiou 3, Kalamaria, Thessaloniki, 55133, Greece. keva@med.auth.gr
European Journal of Pediatrics
|February 27, 2010
Summary
Lemierre syndrome, a severe complication of throat infections, can lead to dangerous septic thrombophlebitis. This case highlights a pediatric Lemierre syndrome caused by Abiotrophia defectiva, successfully treated with antibiotics and anticoagulation.
Area of Science:
- Infectious Diseases
- Vascular Surgery
- Pediatric Critical Care
Background:
- Lemierre syndrome, or postanginal sepsis, is a rare but serious complication of oropharyngeal infections.
- It is characterized by septic thrombophlebitis of the internal jugular vein and potential septicemia.
- Prompt diagnosis and management are crucial due to the risk of metastatic infections.
Observation:
- A previously healthy 12-year-old boy presented with Lemierre syndrome.
- The condition was secondary to a subcutaneous neck abscess.
- The causative agent identified was streptococci, specifically Abiotrophia defectiva.
Findings:
- The patient developed metastatic sequelae, indicating systemic spread of infection.
- Treatment involved a combination of antibiotics (clindamycin and vancomycin) and low molecular weight heparin.
- The therapeutic regimen led to an uneventful recovery.
Implications:
- This case underscores the importance of recognizing Lemierre syndrome in pediatric patients presenting with neck infections.
- Early antibiotic and anticoagulant therapy can significantly improve outcomes.
- Abiotrophia defectiva should be considered in the differential diagnosis of oropharyngeal infections leading to Lemierre syndrome.
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