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Carcinoma erysipeloides.

L R Lever1, P J Holt

  • 1Department of Dermatology, University Hospital of Wales, Heath Park, Cardiff, U.K.

The British Journal of Dermatology
|March 1, 1991
PubMed
Summary
This summary is machine-generated.

This case study highlights carcinoma erysipeloides, a rare skin manifestation linked to an undetected breast carcinoma. Immunohistochemistry confirmed the breast origin of the metastatic tumor.

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Area of Science:

  • Dermatopathology
  • Oncology
  • Medical Diagnostics

Background:

  • Carcinoma erysipeloides is an uncommon cutaneous metastasis.
  • It can present as the initial sign of an occult malignancy.
  • Early diagnosis is crucial for patient prognosis.

Observation:

  • An 83-year-old woman presented with clinical signs of carcinoma erysipeloides.
  • Skin biopsies were obtained for histopathological examination.
  • The patient had no initially apparent primary tumor source.

Findings:

  • Immunohistochemical analysis of skin biopsy specimens revealed positivity for S-100 protein.
  • Reactivity for human milk fat globule antigen (HMFG) was also observed.
  • These markers indicated a metastatic carcinoma originating from the breast.

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Implications:

  • This case underscores the importance of considering metastatic disease in patients with carcinoma erysipeloides.
  • Immunohistochemistry plays a vital role in identifying the primary tumor site.
  • Prompt diagnosis and treatment of the underlying breast cancer can improve outcomes.