Related Experiment Video
Updated: Jun 15, 2026

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
Congenital intrinsic intestinal obstruction in a Caribbean country
Trevor I Anatol1, Seetharaman Hariharan
1Department of Clinical Surgical Sciences, Faculty of Medical Sciences, St. Augustine Campus, University of the West Indies, Trinidad and Tobago. trevana@wow.net
Insights
Congenital intrinsic intestinal obstruction in infants is a serious condition with a high complication rate (68.2%) and mortality (27.3%). Effective perioperative management of prematurity and sepsis is crucial for improving outcomes.
Area of Science:
- Pediatric Surgery
- Neonatal Medicine
- Gastrointestinal Surgery
Background:
- Congenital intrinsic intestinal obstruction presents a significant challenge in pediatric surgery.
- Understanding its clinical characteristics and outcomes is vital for developing effective treatment strategies.
Purpose of the Study:
- To evaluate the clinical features, perioperative aspects, and outcomes of congenital intrinsic intestinal obstruction in infants.
- To compare findings with existing international literature.
Main Methods:
- Retrospective data collection from 1999-2006.
- Inclusion of infants diagnosed with congenital intrinsic bowel obstruction.
- Analysis of demographic, perioperative, surgical, and outcome data.
Main Results:
- Twenty-two infants were treated, with an incidence of 3.14 per 10,000 live births.
- Duodenal lesions were more common than jejuno-ileal lesions (1.5:1 ratio).
- High complication (68.2%) and mortality (27.3%) rates were observed.
Conclusions:
- Lower gestational age, elevated leukocyte count, and distal small bowel obstruction were linked to mortality.
- Improved outcomes necessitate enhanced perioperative management of prematurity and sepsis.
Abstract:
This study was undertaken to evaluate the clinical characteristics, perioperative features, and outcome of congenital intrinsic intestinal obstruction in a developing Caribbean country for comparison with previous literature reports. This study included retrospective data collection on all infants referred to the hospital with a diagnosis of congenital intrinsic bowel obstruction during the period 1999-2006. Data studied were demographic features, perioperative details, surgical procedures performed, postoperative course, and early outcome. Twenty-two infants were treated, with an incidence of 3.14 per 10,000 live births. Duodenal outnumbered jejuno-ileal lesions by 1.5 to 1. Complications occurred in 68.2% of cases, and the mortality rate was 27.3%. Lower gestational age, a high leukocyte count, and more distal small bowel obstruction were significantly associated with mortality. Improvement in the outcome of surgical treatment of this problem in this population requires more effective perioperative management of prematurity and sepsis.
Related Concept Videos
Intestinal Obstruction I: Introduction
Intestinal Obstruction II: Pathophysiology
Pyloric Obstruction
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Esophageal Strictures-I: Introduction
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...