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Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
Triterpenoids from Angiopteris palmiformis
Chiy-Rong Chen1, Yun-Wen Liao, Hui-Ting Wu
1Department of Biological Science and Technology, Meiho Institute of Technology, Pingtung 91201, Taiwan.
Chemical & Pharmaceutical Bulletin
|March 2, 2010
Summary
Researchers identified five triterpenoids from Angiopteris palmiformis leaves, including four novel compounds. These fernane and filicane triterpenoids expand our knowledge of plant natural products.
Area of Science:
- Natural Product Chemistry
- Phytochemistry
- Organic Chemistry
Background:
- Angiopteris palmiformis is a fern species with potential for novel bioactive compound discovery.
- Triterpenoids are a diverse class of natural products with various biological activities.
Purpose of the Study:
- To isolate and characterize new triterpenoids from the leaves of Angiopteris palmiformis.
- To contribute to the understanding of the chemical diversity of fern natural products.
Main Methods:
- Extraction of plant material using methyl alcohol.
- Isolation of compounds using chromatographic techniques.
- Structure elucidation using Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS), and Infrared (IR) spectroscopy.
Main Results:
- Isolation of two new fernane triterpenoids: 7alpha-hydroxyfern-8-en-11-one (1) and 11beta-hydroxyfern-8-en-7-one (2).
- Isolation of two new filicane triterpenoids: 3beta-hydroxyfilic-4(23)-ene (3) and filicenol (5).
- Isolation of one known filicane triterpenoid: 3alpha-hydroxyfilic-4(23)-ene (4).
Conclusions:
- The study successfully identified and characterized novel triterpenoids from Angiopteris palmiformis.
- The findings enhance the knowledge of fernane and filicane triterpenoid structures and their occurrence in ferns.
