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Published on: May 1, 2021
Pathogenesis of contact lens-associated microbial keratitis
Suzanne M J Fleiszig1, David J Evans
1School of Optometry and Graduate Programs in Vision Science, Microbiology, Infectious Disease and Immunity, and Health and Medical Sciences, University of California-Berkeley, Berkeley, CA, USA. fleiszig@berkeley.edu
Abstract:
Sight-threatening microbial keratitis associated with contact lens wear remains a serious concern for patients, eye-care practitioners, and the contact lens industry. Several decades of research and some major advances in lens and solution technology have not resulted in a decline in disease incidence. Here, we offer a perspective on the complex pathogenesis of microbial keratitis, the factors that have prevented a better understanding of this disease, and new approaches being used to tackle this important clinical problem.
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