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Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
Published on: December 3, 2019
Operations about hip in human immunodeficiency virus-positive patients
Jeong Joon Yoo1, Sae Hyung Chun, Young Sam Kwon
1Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul, Korea.
Hip surgeries in human immunodeficiency virus (HIV)-infected patients are safe and effective when performed with optimal preoperative immunity and adherence to infection control guidelines. These procedures showed no immediate complications, ensuring patient and medical staff safety.
Area of Science:
- Orthopedic Surgery
- Infectious Diseases
- Virology
Background:
- Increasing prevalence of human immunodeficiency virus (HIV) infections.
- High incidence of osteonecrosis of the femoral head in HIV-infected patients.
- Need for safe surgical protocols for HIV-positive individuals.
Purpose of the Study:
- To report surgical outcomes in HIV-infected patients undergoing hip procedures.
- To evaluate the safety and efficacy of orthopedic surgery in this population.
- To assess adherence to HIV infection control guidelines during surgery.
Main Methods:
- Retrospective review of 5 HIV-infected patients undergoing hip surgery (2005-2007).
- Procedures included bone grafting, screw fixation, total hip arthroplasty, and multiple drilling.
- Adherence to Korea Centers for Disease Control and Prevention HIV infection control guidelines.
Main Results:
- Successful bony union achieved with autologous bone grafting.
- Significant functional improvements observed after total hip replacement arthroplasty.
- No immediate postoperative complications like infection; one late mortality unrelated to surgery.
Conclusions:
- Orthopedic hip surgery is safe for HIV-infected patients with optimal preoperative immunity.
- Adherence to infection control guidelines ensures the safety of medical personnel.
- Surgical interventions can lead to positive functional outcomes in HIV-infected patients.
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