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Urolithiasis in patients suffering from malignant hematologic diseases.
Sae Woong Kim1, Sung Dae Kim, Je Mo Yoo
1Department of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Yonsei Medical Journal
|March 2, 2010
Summary
Malignant hematologic diseases significantly increase the risk of urolithiasis (kidney stones). These patients also show a higher prevalence of radiolucent stones compared to the general population.
Area of Science:
- Nephrology
- Hematology
- Oncology
Background:
- Urolithiasis is a common condition.
- Malignant hematologic diseases encompass a range of blood cancers.
- The relationship between hematologic malignancies and urolithiasis requires further investigation.
Purpose of the Study:
- To determine the incidence of urolithiasis in patients with malignant hematologic diseases.
- To characterize the types of kidney stones (radiopacity) in this patient group.
Main Methods:
- A retrospective study comparing 901 patients with malignant hematologic diseases to 40,543 emergency room patients.
- Malignant hematologic disease patients were stratified into two groups based on treatment: chemotherapy/steroids (Group I) or blood transfusions (Group II).
- Incidence and radiopacity of urolithiasis were compared between groups.
Main Results:
- Urolithiasis incidence was significantly higher in malignant hematologic patients (3.2%) versus controls (1.4%).
- Patients with malignant hematologic diseases had a significantly higher rate of radiolucent stones (46.6%) compared to controls (16.3%).
Conclusions:
- Malignant hematologic patients exhibit a significantly elevated risk of developing urolithiasis.
- The stone composition in malignant hematologic patients tends towards radiolucent types.
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