[Aflatoxin contamination of food: additional risk factor for chronic liver diseases]
C Huţanaşu1, C Sfarti, Anca Trifan
1Facultatea de Medicină, Institutul de Gastroenterologie si Hepatologie, Universitatea de Medicină si Farmacie "Gr.T. Popa" Iaşi.
Unlabelled:
Aflatoxins are over all spread toxic metabolites of fungi, able to induce chronic liver damages.
Aim:
To establish the correlation between the degree of liver disease and risk of chronic intake of aflatoxin contaminated foods.
Material And Method:
123 patients divided in three groups (controls, chronic hepatitis and liver cirrhosis) completed a food frequency questionaire (FFQ) estimating the intake risk of foods with a high potential of contamination with aflatoxins and alcohol consumption.
Results:
Frequent intake of high risk foodstuff was declared by 37% of the participants, without any differences between the three groups. Foods with a very high risk of contamination were more frequently consumed in rural areas (predominant maize and oily seeds), while in the urban areas spices and coffee prevailed. In countryside, the feeding risk decreased with the gravity of liver disease, but alcohol consumption was significantly greater.
Conclusion:
FFQ revealed a high risk of ingestion of aflatoxin contaminated foodstuff in general population, greater in rural areas. The risk of aflatoxin intake seems unreleated with the gravity of chronic liver disease.
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