Related Experiment Video
Updated: Jun 15, 2026
Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
Published on: July 18, 2016
[Expression of CA-125 in ovarian cancer]
Ramona Mircea1, Doina Lucia Frîncu, F Dumitrache
1Facultatea de Mediciă, Catedra de Stiinţe Morfologice, Universitatea de Medicini si Farmacie "Gr.T. Popa" Iaşi.
Unlabelled:
Ovarian carcinoma is a heterogeneus disease. Pathologists classify it in serous, clear cell, endometrioid and mucinos subtypes. Each of these subtypes is associated with different genetic risk factors and molecular events during oncogenesis and it is characterised by distinct mRNA expression profiles.
Material And Method:
We have studied 55 pacients with ovarian tumours who underwent surgery in Clinic "Elena Doamna", Iaşi between 2005-2008. CA-125 value was determined pre or postoperator.
Results:
We have investigated the relationship between tumoral type and CA125 value in all studied cases.
Conclusions:
By demonstrating the correlations between biomarker expression with stage or prognosis and by demonstrating the variation in expression rates between subtypes we offer persuasive evidence supporting the view that ovarian carcinoma subtypes are different diseases and the value of the biomarker is not always correlated with malignancy.
