Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Physical Methods for Controlling Microbial Growth: Temperature

Physical Methods for Controlling Microbial Growth: Temperature

Heat is a widely used method to control microbial growth by targeting and denaturing cellular proteins, thereby killing or inactivating microbes. This method's effectiveness is quantified using parameters such as the thermal death point (TDP), thermal death time (TDT), and decimal reduction time (D value). TDP represents the lowest temperature at which all microorganisms in a liquid suspension are eliminated within 10 minutes, whereas TDT is the time necessary to achieve sterilization at a...

Temperature and Thermal Equilibrium

Temperature and Thermal Equilibrium

Heat and temperature are essential concepts for everyone every day. The study of heat and temperature is part of an area of physics known as thermodynamics. It is not always easy to distinguish heat and temperature.
The concept of temperature has evolved from the common concepts of hot and cold. The scientific definition of temperature explains more than just our sense of hot and cold. Temperature is operationally defined as the quantity measured with a thermometer. Furthermore, temperature is...

Constant Volume Calorimetry

Constant Volume Calorimetry

Calorimeters are useful to determine the heat released or absorbed by a chemical reaction. Coffee cup calorimeters are designed to operate at constant (atmospheric) pressure and are convenient to measure heat flow (or enthalpy change) accompanying processes that occur in solution at constant pressure. A different type of calorimeter that operates at constant volume, colloquially known as a bomb calorimeter, is used to measure the energy produced by reactions that yield large amounts of heat and...

Constant Pressure Calorimetry

Constant Pressure Calorimetry

Calorimetry is a technique used to measure the amount of heat involved in a chemical or physical process or to measure the heat transferred to or from a substance. The heat is exchanged with a calibrated and insulated device called the calorimeter. Calorimetry experiments are based on the assumption that there is no heat exchange between the insulated calorimeter and the external environment. The well-insulated calorimeters prevent the transfer of heat between the calorimeter and its external...

Bioreactor Controls-III

Bioreactor Controls-III

Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...

Bioreactor Controls-II

Bioreactor Controls-II

In aerobic fermentations, oxygen is vital for microbial growth and metabolite production. Since air comprises only about 20% oxygen and the gas is poorly soluble in water—just 9 ppm at 20°C—supplying sufficient oxygen becomes a critical challenge, especially in high-demand processes like yeast growth or citric acid production. Even a fully saturated broth may offer only a few seconds of oxygen availability.To address this, sterile or scrubbed air is introduced into the fermentor via a sparger...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Search for the K_{L}→π^{0}νν[over ¯] Decay at the J-PARC KOTO Experiment.

Physical review letters·2025

Same author

Search for the Pair Production of Dark Particles X with K_{L}^{0}→XX, X→γγ.

Physical review letters·2023

Same author

Adaptation of the microdosimetric kinetic model to hypoxia.

Physics in medicine and biology·2016

Same author

Two-chamber configuration of Bio-Nano electron cyclotron resonance ion source for fullerene modification.

The Review of scientific instruments·2016

Same author

Recent developments of ion sources for life-science studies at the Heavy Ion Medical Accelerator in Chiba (invited).

The Review of scientific instruments·2016

Same author

Development of a compact ECR ion source for various ion production.

The Review of scientific instruments·2016

Search research articles

Related Experiment Video

Updated: Jun 15, 2026

Temperature-programmed Deoxygenation of Acetic Acid on Molybdenum Carbide Catalysts

Temperature-programmed Deoxygenation of Acetic Acid on Molybdenum Carbide Catalysts

Published on: February 7, 2017

MIVOC method with temperature control.

W Takasugi¹, M Wakaisami, N Sasaki

¹Accelerator Engineering Corporation, 3-8-5 Konakadai, Inage, Chiba 263-0043, Japan. aec2g@nirs.go.jp

The Review of Scientific Instruments

|March 3, 2010

Summary

Researchers developed a new method to produce rare metal ions for experiments using volatile compounds and precise temperature control. This technique conserves expensive materials for advanced research applications.

More Related Videos

Controlling Flow Speeds of Microtubule-Based 3D Active Fluids Using Temperature

Controlling Flow Speeds of Microtubule-Based 3D Active Fluids Using Temperature

Published on: November 26, 2019

A Machine-Vision Approach to Transmission Electron Microscopy Workflows, Results Analysis and Data Management

A Machine-Vision Approach to Transmission Electron Microscopy Workflows, Results Analysis and Data Management

Published on: June 23, 2023

Related Experiment Videos

Last Updated: Jun 15, 2026

Temperature-programmed Deoxygenation of Acetic Acid on Molybdenum Carbide Catalysts

Temperature-programmed Deoxygenation of Acetic Acid on Molybdenum Carbide Catalysts

Published on: February 7, 2017

Controlling Flow Speeds of Microtubule-Based 3D Active Fluids Using Temperature

Controlling Flow Speeds of Microtubule-Based 3D Active Fluids Using Temperature

Published on: November 26, 2019

A Machine-Vision Approach to Transmission Electron Microscopy Workflows, Results Analysis and Data Management

A Machine-Vision Approach to Transmission Electron Microscopy Workflows, Results Analysis and Data Management

Published on: June 23, 2023

Area of Science:

Physics
Chemistry
Materials Science

Background:

The Heavy Ion Medical Accelerator in Chiba (HIMAC) has utilized various ion species for cancer therapy and scientific research since 1994.
Electron cyclotron resonance ion sources typically produce ions from gases, but some species are difficult to generate this way.
The sputtering method is used for difficult-to-produce ions but is inefficient for rare and expensive isotopes.

Purpose of the Study:

To develop a more efficient method for producing rare and expensive metal ions.
To reduce material consumption rates for producing specific ion species.
To enable the generation of a wider range of ions for experimental purposes.

Main Methods:

Investigated the "metal ions from volatile compounds method" for ion production.
Tested a variety of volatile compounds suitable for ion generation.
Developed an accurate temperature control system to optimize vapor pressure for each compound.

Main Results:

Successfully produced various metal ions, including (58)Fe(9+), Co(9+), Mg(5+), Ti(10+), Si(5+), and Ge(12+).
Demonstrated the effectiveness of the temperature control system in achieving optimal vapor pressure for ion production.
Showcased a viable alternative to sputtering for producing challenging ion species.

Conclusions:

The "metal ions from volatile compounds method" with precise temperature control is effective for producing rare metal ions.
This method offers a solution for reducing material consumption, especially for valuable isotopes.
The developed technique expands the capabilities of ion sources for diverse scientific applications.