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Updated: Jun 15, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Multiple-suture nonsyndromic craniosynostosis: early and effective management using endoscopic techniques.
David F Jimenez1, Constance M Barone
1Department of Neurosurgery, The University of Texas Health Science Center at San Antonio, Texas, USA. jimenezd3@uthscsa.edu
Minimally invasive endoscopic surgery effectively treats multiple-suture nonsyndromic craniosynostosis in infants. This technique, combined with cranial molding, corrects deformities safely with excellent outcomes.
Area of Science:
- Pediatric Neurosurgery
- Craniofacial Surgery
- Minimally Invasive Surgery
Background:
- Nonsyndromic craniosynostosis involving multiple sutures requires effective treatment strategies.
- Endoscopy-assisted techniques offer a less invasive approach compared to traditional open surgery.
Observation:
- A study evaluated 21 infants with multiple-suture nonsyndromic craniosynostosis treated with endoscopy-assisted craniectomies and postoperative cranial orthoses.
- The most frequently treated sutures were coronal, sagittal, metopic, and lambdoid.
Findings:
- Endoscopic treatment resulted in no deaths, with a mean follow-up of 61 months.
- Significant correction of deformities like brachycephaly, vertical dystopia, and nasal deviation was observed.
- Mean blood loss was 42 ml, mean hospital stay was 1 day, and the intraoperative transfusion rate was 0%.
Implications:
- Endoscopic techniques provide a safe and effective surgical alternative for complex craniosynostosis.
- Early intervention with this method leads to excellent correction of skull base and craniofacial abnormalities.
- This approach minimizes surgical trauma and hospital stay for pediatric patients.
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