Related Experiment Video

Updated: Jun 15, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
05:26

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Published on: May 28, 2019

Contrast medium nephrotoxicity after renal artery and coronary angioplasty

Paolo Marraccini1, Massimiliano Bianchi, Enza Fommei

  • 1CNR Institute of Clinical Physiology of Pisa, Italy. paolomar@ifc.cnr.it

Acta Radiologica (Stockholm, Sweden : 1987)
|March 3, 2010
PubMed

Insights

Patients undergoing renal angioplasty (PTRA) show less susceptibility to kidney damage from contrast media (CM) compared to those receiving percutaneous coronary intervention (PCI). PTRA

Area of Science:

  • Nephrology
  • Interventional Cardiology
  • Radiology

Background:

  • Contrast media (CM) administration can cause renal dysfunction, potentially limiting the benefits of interventional procedures.
  • Patients undergoing renal angioplasty (PTRA) are at risk for contrast-induced nephropathy.
  • Comparing CM nephrotoxicity in PTRA versus percutaneous coronary intervention (PCI) is crucial for patient management.

Purpose of the Study:

  • To compare the susceptibility to the nephrotoxic effects of CM in patients undergoing PTRA versus PCI.
  • To assess the impact of CM on renal function in different interventional procedures.

Main Methods:

  • A comparative study involving 33 patients undergoing PTRA and 33 patients undergoing PCI.
  • Patients were matched for baseline creatinine, gender, and age.
  • Postprocedural serum creatinine levels were measured 48 hours after the intervention.

Main Results:

  • Serum creatinine nonsignificantly decreased in the PTRA group but significantly increased in the PCI group.
  • Changes in serum creatinine differed significantly between the PTRA and PCI groups.
  • The observed differences were not attributable to clinical risk profiles or CM volume.

Conclusions:

  • Patients undergoing PTRA demonstrated lower susceptibility to CM-induced renal damage compared to PCI patients.
  • CM toxicity appears to have minimal influence on the effectiveness of PTRA concerning renal function.
  • This preliminary study suggests a potential protective effect or lower risk in PTRA patients regarding CM nephrotoxicity.
Abstract

More Related Videos

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

Related Concept Videos

Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Cardiac Catheterization IV: Nursing Management01:26

Cardiac Catheterization IV: Nursing Management

Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...