Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Genomics

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

Evolutionary Relationships through Genome Comparisons

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...

Genome Annotation and Assembly

Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.

Next-generation Sequencing

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.

Modern Molecular Taxonomy

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...

The Central Dogma

The Central Dogma

The central dogma explains the flow of genetic information from DNA nucleotides to the amino acid sequence of proteins.
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

LGBTQ+ Students' Experiences of Misnaming in Swedish Secondary Schools.

Healthcare (Basel, Switzerland)·2026

Same author

Correction: MethylSeqLogo: DNA methylation smart sequence logos.

BMC bioinformatics·2025

Same author

Prediction of mitochondrial targeting signals and their cleavage sites.

Methods in enzymology·2024

Same author

MethylSeqLogo: DNA methylation smart sequence logos.

BMC bioinformatics·2024

Same author

Effects of spaced k-mers on alignment-free genotyping.

Bioinformatics (Oxford, England)·2023

Same author

Assessment of Clinical Response Following Atezolizumab and Bevacizumab Treatment in Patients With Neuroendocrine Tumors: A Nonrandomized Clinical Trial.

JAMA oncology·2022

Search research articles

Related Experiment Video

Updated: Jun 15, 2026

Introductory Analysis and Validation of CUT&RUN Sequencing Data

Introductory Analysis and Validation of CUT&RUN Sequencing Data

Published on: December 13, 2024

Genome informatics: advances in theory and practice.

Szu-Chin Fu¹, Paul Horton

¹Computational Biology Research Center, AIST, and The University of Tokyo, Graduate School of Frontier Sciences, 2-42 Aomi, Tokyo, 135-0064, Japan. szuchin.fu@gmail.com.

Genome Medicine

|March 3, 2010

Summary

The 20th International Conference on Genome Informatics (ICGI) in Yokohama, Japan, convened experts to discuss advancements in genomic data analysis and interpretation. Key discussions focused on emerging technologies and computational approaches shaping the future of genomics research.

More Related Videos

Transcriptomic Analysis of C. elegans RNA Sequencing Data Through the Tuxedo Suite on the Galaxy Project

Transcriptomic Analysis of C. elegans RNA Sequencing Data Through the Tuxedo Suite on the Galaxy Project

Published on: April 8, 2017

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

Related Experiment Videos

Last Updated: Jun 15, 2026

Introductory Analysis and Validation of CUT&RUN Sequencing Data

Introductory Analysis and Validation of CUT&RUN Sequencing Data

Published on: December 13, 2024

Transcriptomic Analysis of C. elegans RNA Sequencing Data Through the Tuxedo Suite on the Galaxy Project

Transcriptomic Analysis of C. elegans RNA Sequencing Data Through the Tuxedo Suite on the Galaxy Project

Published on: April 8, 2017

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

Area of Science:

Genomics
Bioinformatics
Computational Biology

Background:

The field of genome informatics is rapidly evolving, driven by technological advancements in DNA sequencing and data generation.
International conferences serve as crucial platforms for disseminating research findings and fostering collaboration.

Purpose of the Study:

To report on the proceedings and key themes of the 20th International Conference on Genome Informatics (ICGI).
To highlight significant advancements and future directions discussed in genome informatics.

Main Methods:

The report is based on observations and summaries of presentations and discussions at the conference.
Keynote addresses, oral presentations, and poster sessions were attended and reviewed.

Main Results:

The conference showcased progress in areas such as next-generation sequencing data analysis, comparative genomics, and systems biology.
Discussions emphasized the growing importance of integrating diverse biological data types for comprehensive genomic insights.
Emerging trends in structural bioinformatics and the application of machine learning in genomics were prominent.

Conclusions:

The 20th ICGI highlighted the dynamic nature of genome informatics and its critical role in modern biological research.
Continued innovation in computational tools and analytical methods is essential for addressing the challenges of large-scale genomic data.