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Updated: Jun 15, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Clinical manifestations and radiological features of hepatopulmonary syndrome.]
Guo Li1, Ju-Hong Shi, Wei-Xuan Lu
1Department of Respiratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China.
Objective:
To investigate the clinical and radiological features of hepatopulmonary syndrome (HPS).
Methods:
Twenty two cases diagnosed as HPS in Peking Union Medical College Hospital from Nov, 1996 to Nov, 2008 were reviewed. Their clinical features and radiological findings were analyzed.
Results:
The study included 12 males and 10 females with a mean age of (44 +/- 17) years and mean course of (54 +/- 52) months. Abnormalities on chest CT scans were found in 12 cases, which included intrapulmonary artery dilatation in 10 cases, with subpleural small nodular, reticular and patchy opacities; bilateral lower basal segmental artery dilatation in 3 cases; main pulmonary artery dilation in 1 case; right ventricular enlargement in 1 case and bilateral pleural effusion in 1 case. The chest CT was normal in 6 cases. CTPA and pulmonary artery angiogram were performed in 15 cases and artery dilatation was found in 4. Diffuse liver diseases were found in 12 cases by CT scans, 10 of them presented as typical hepatic cirrhosis and 2 cases as liver hepatomegaly, while esophagus varix and(or) fundus gastricus varix were found in 12 cases and splenomegaly in 6 cases, hydroperitonia in 3 cases.
Conclusion:
Clinical manifestations combined with CT features were helpful for the diagnosis of HPS.
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