Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk for Autism Across Generations.

Biological psychiatry·2026
Same author

Cardiometabolic Biomarkers at Age 44-45 in the Psychosis Spectrum: The British National Child Development Study.

Schizophrenia bulletin·2026
Same author

Cognitive impairment preceding the onset of the first psychosis episode in schizophrenia.

Molecular psychiatry·2026
Same author

Perinatal and maternal factors associated with Autism Spectrum Disorder.

PloS one·2026
Same author

Social Isolation and Aging health in Schizophrenia spectrum disorders (SIAS): study protocol for a multinational longitudinal study.

BMC psychiatry·2026
Same author

Whole brain grey matter synaptic terminal density, age and intellectual functioning in schizophrenia: an in vivo [<sup>11</sup>C]UCB-J positron emission tomography study.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026

Related Experiment Video

Updated: Jun 15, 2026

Development and Implementation of a Multi-Disciplinary Technology Enhanced Care Pathway for Youth and Adults with Concussion
08:13

Development and Implementation of a Multi-Disciplinary Technology Enhanced Care Pathway for Youth and Adults with Concussion

Published on: January 20, 2019

Deconstructing processing speed deficits in schizophrenia: application of a parametric digit symbol coding test.

Peter Bachman1, Abraham Reichenberg, Patrick Rice

  • 1Department of Psychiatry & Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA 90095, USA. bachman@psych.ucla.edu

Schizophrenia Research
|March 3, 2010
PubMed
Summary

Schizophrenia patients show cognitive processing inefficiency, particularly in tasks requiring memory. This memory impairment significantly impacts their ability to use predictable information, affecting overall cognitive function.

More Related Videos

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

A Semantic Priming Event-related Potential (ERP) Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder
08:17

A Semantic Priming Event-related Potential (ERP) Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder

Published on: April 12, 2018

Related Experiment Videos

Last Updated: Jun 15, 2026

Development and Implementation of a Multi-Disciplinary Technology Enhanced Care Pathway for Youth and Adults with Concussion
08:13

Development and Implementation of a Multi-Disciplinary Technology Enhanced Care Pathway for Youth and Adults with Concussion

Published on: January 20, 2019

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

A Semantic Priming Event-related Potential (ERP) Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder
08:17

A Semantic Priming Event-related Potential (ERP) Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder

Published on: April 12, 2018

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Psychiatry

Background:

  • Cognitive processing inefficiency is a key marker for schizophrenia, impacting illness severity and daily functioning.
  • Digit symbol coding tasks reveal significant neuropsychological deficits in schizophrenia patients.
  • The specific cognitive processes contributing to coding deficits in schizophrenia remain under-explored.

Purpose of the Study:

  • To investigate the role of visual scanning efficiency and relational memory in cognitive processing for schizophrenia.
  • To isolate the impact of memory and visual scanning on a computerized digit symbol coding task.
  • To understand how cognitive processing speed is affected by memory impairments in schizophrenia.

Main Methods:

  • Developed a novel computerized digit symbol coding task to manipulate visual scanning and relational memory demands.
  • Kept decisional and motor requirements constant across task variations.
  • Compared performance of schizophrenia patients (n=85) with healthy controls (n=30).

Main Results:

  • Schizophrenia patients were impaired across all task aspects compared to healthy controls.
  • Patients demonstrated a significant inability to benefit from predictable target information.
  • This deficit suggests memory impairment impacts broader cognitive processing.

Conclusions:

  • Memory deficits in schizophrenia have far-reaching consequences beyond traditional memory domains.
  • Impaired cognitive processing speed in schizophrenia is linked to underlying memory impairments.
  • Further research into mnemonic deficits is crucial for understanding schizophrenia's cognitive landscape.