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Related Concept Videos

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
Genome Annotation and Assembly03:36

Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
Gene Families01:57

Gene Families

Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
Gene Families01:57

Gene Families

Gene families consist of groups of genes proposed to have originated from a common ancestor. Typically these arise through events in which a gene or genes are mistakenly duplicated during cell division. Unlike their parent genes (which are subject to selection pressure to maintain function), these gene copies do not need to preserve their sequences and may evolve at a relatively faster rate.
Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...

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Related Experiment Video

Updated: Jun 15, 2026

Pattern-based Search of Epigenomic Data Using GeNemo
06:38

Pattern-based Search of Epigenomic Data Using GeNemo

Published on: October 8, 2017

Using WebGBrowse to visualize genome annotation on GBrowse.

Ram Podicheti1, Qunfeng Dong

  • 1Center for Genomics and Bioinformatics, Indiana University, Bloomington, IN 47405, USA.

Cold Spring Harbor Protocols
|March 3, 2010
PubMed
Summary
This summary is machine-generated.

WebGBrowse simplifies genome visualization for biologists by providing an easy-to-use web server. It allows users to upload annotation files and configure genomic feature displays with the integrated GBrowse software.

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Area of Science:

  • Bioinformatics
  • Genomics
  • Computational Biology

Background:

  • Genomic visualization tools like GBrowse are essential for analyzing biological data.
  • Installation and configuration of GBrowse can be complex and time-consuming for researchers.

Purpose of the Study:

  • To introduce WebGBrowse, a web server designed to simplify genome annotation visualization.
  • To provide a user-friendly protocol for biologists to utilize WebGBrowse.

Main Methods:

  • WebGBrowse accepts user-supplied annotation files.
  • The server guides users through configuring the display of genomic features.
  • Integrated GBrowse software facilitates visualization.

Main Results:

  • WebGBrowse offers an accessible platform for genome annotation visualization.
  • The protocol effectively guides users through the WebGBrowse workflow.

Conclusions:

  • WebGBrowse significantly lowers the barrier to entry for genomic data visualization.
  • This tool empowers biologists to analyze and interpret genomic data more efficiently.