Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cushing Syndrome I: Introduction

Cushing Syndrome I: Introduction

Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the syndrome.Exogenous...

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

Pulmonary Tuberculosis V

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

Pulmonary Tuberculosis II

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

COPD: Pathogenesis and Clinical Features

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Impact of Socioeconomic Factors on Pediatric Keratoplasty Outcomes: A Decade of Our Experience at a Tertiary Eye Care Center in South India.

Cornea·2026

Same author

Risk factors for early emulsification of silicone oil after surgery for rhegmatogenous retinal detachment.

Indian journal of ophthalmology·2026

Same author

Expert Opinion on the First-Line Management of Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema in India: The Role of Faricimab.

Cureus·2026

Same author

Scleral buckling in stage 4A/B retinopathy of prematurity: A retrospective analysis of 105 eyes.

Indian journal of ophthalmology·2026

Same author

Diagnostic and Therapeutic Challenges.

Retina (Philadelphia, Pa.)·2025

Same author

Long-term results of surgery for retinal detachment due to retinopathy of prematurity.

Indian journal of ophthalmology·2025

Search research articles

Related Experiment Video

Updated: Jun 15, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Coats' disease: an Indian perspective.

Pukhraj Rishi¹, Ekta Rishi, Mahesh Uparkar

¹Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, 18, College Road, Chennai-600 006, India.

Indian Journal of Ophthalmology

|March 3, 2010

Summary

Coats' disease in Indian patients often presents with severe vision loss and extensive retinal exudation, predominantly affecting males. Early detection and treatment are crucial for better anatomical and structural outcomes.

Related Experiment Videos

Last Updated: Jun 15, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Area of Science:

Ophthalmology
Retinal Diseases
Pediatric Ophthalmology

Background:

Coats' disease is a rare idiopathic condition characterized by retinal telangiectasia and exudation.
It typically affects young males and can lead to significant vision impairment and blindness.

Purpose of the Study:

To delineate the clinical characteristics, management strategies, and treatment outcomes for Coats' disease in a large cohort of Indian patients.
To identify specific features and outcomes in this population compared to global data.

Main Methods:

A retrospective chart review was conducted on 280 patients (307 eyes) diagnosed with Coats' disease.
Data collection spanned from January 1996 to January 2006 at a single tertiary referral center in southern India.

Main Results:

The study included 280 patients (307 eyes) with a mean age of 15.67 years. Presenting features included decreased vision (77%), unilateral involvement (90%), and male predominance (83.4%).
Retinal telangiectasia (99%), exudation (89%), and retinal detachment (51.5%) were common. Severe visual impairment (<20/200) was noted in 80.9% of eyes.
Favorable anatomical and structural outcomes were achieved in 61.93% and 74% of treated eyes, respectively. Complications included phthisis bulbi (7%) and neovascular glaucoma (5%).

Conclusions:

Indian patients with Coats' disease exhibit a pronounced male predominance and frequently present with severe visual impairment and extensive exudation.
Distinctive features in this cohort include anterior segment involvement, pain, and vitreous hemorrhage, highlighting regional variations in disease presentation.