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Updated: Jun 15, 2026

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement
Published on: February 22, 2022
High-intensity training versus traditional exercise interventions for promoting health
Lars Nybo1, Emil Sundstrup, Markus D Jakobsen
1Department of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark.
Brief intense interval training (INT) significantly improves cardiorespiratory fitness and glucose tolerance. However, prolonged exercise is more effective for reducing fat and improving cholesterol, while strength training builds muscle mass.
Area of Science:
- Exercise Physiology
- Sports Science
- Human Health
Background:
- Exercise interventions are crucial for health promotion.
- Comparing different training modalities like interval, prolonged, and strength training is important for optimizing health outcomes.
- Understanding the specific benefits of each training type can guide personalized exercise prescriptions.
Purpose of the Study:
- To assess the effectiveness of brief intense interval training (INT) for health promotion.
- To compare the health benefits of INT with prolonged exercise and strength training.
- To evaluate INT's impact on cardiorespiratory fitness, glucose metabolism, body composition, and lipid profiles.
Main Methods:
- Thirty-six untrained men participated in a 12-week study.
- Intervention groups included intense interval running (INT; 40 min/week), prolonged running (~150 min/week), and strength training (~150 min/week).
- A control group maintained their habitual lifestyle.
Main Results:
- INT demonstrated superior improvement in cardiorespiratory fitness (VO2max) compared to other groups.
- Both INT and prolonged running improved glucose tolerance.
- Prolonged running was more effective than INT for reducing resting heart rate, body fat, and improving cholesterol ratios. Strength training increased lean and total body mass.
Conclusions:
- Twelve weeks of INT effectively enhances cardiorespiratory fitness and glucose tolerance.
- INT is less effective than prolonged training for managing hyperlipidemia and obesity.
- INT does not impact muscle or bone health, unlike strength training.
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