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Updated: Jun 15, 2026

Modeling an Enzyme Active Site using Molecular Visualization Freeware
Published on: December 25, 2021
Visualization of macromolecular structures
Seán I O'Donoghue1, David S Goodsell, Achilleas S Frangakis
1European Molecular Biology Laboratory, Heidelberg, Germany. sean.odonoghue@embl.de
Abstract:
Structural biology is rapidly accumulating a wealth of detailed information about protein function, binding sites, RNA, large assemblies and molecular motions. These data are increasingly of interest to a broader community of life scientists, not just structural experts. Visualization is a primary means for accessing and using these data, yet visualization is also a stumbling block that prevents many life scientists from benefiting from three-dimensional structural data. In this review, we focus on key biological questions where visualizing three-dimensional structures can provide insight and describe available methods and tools.
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