Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 15, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery
05:39

Non-Intubated Video-Assisted Thoracoscopic Surgery

Published on: May 26, 2023

Standard versus video-assisted thyroidectomy: objective postoperative pain evaluation.

Paolo Miccoli1, Rocco Rago, Marco Massi

  • 1Department of Surgery, University of Pisa, Via Roma 67, 56126, Pisa, Italy.

Surgical Endoscopy
|March 3, 2010
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ERAS thyroidectomy within the Italian DRG-based public health system: surgical efficiency is penalized.

Updates in surgery·2026
Same author

Lactic acid promotes metastasis of papillary thyroid carcinoma by enhancing CPT1A lactylation.

Cell death & disease·2026
Same author

Simulation unlocked: transforming thyroid surgery training through high-fidelity and curriculum-based innovation-a systematic review.

Langenbeck's archives of surgery·2026
Same author

MYELOstudy: lymph node stage of aggressiveness in medullary thyroid cancer-a retrospective multi-center study analysis.

Updates in surgery·2026
Same author

Access to Fertility Preservation Counselling for Young Women with Haematological Malignancies: Incidence-Adjusted Trends from the Italian PreFerIta Network (2015-2023).

Journal of clinical medicine·2026
Same author

Implantation of cancer cells from transoral endoscopic thyroidectomy: a case report.

Gland surgery·2026
Same journal

Efficacy and safety of transoral incisionless fundoplication in non-obese and obese adults: a population-based cohort study from the United States.

Surgical endoscopy·2026
Same journal

Minimally invasive versus open surgery for adhesive small bowel obstruction: a systematic review and meta-analysis.

Surgical endoscopy·2026
Same journal

Enhanced view/extended totally extraperitoneal plasty (eTEP) Rives-Stoppa repair versus open Rives-Stoppa repair: a single-center retrospective propensity score-matched cohort study.

Surgical endoscopy·2026
Same journal

Robotic-assisted endoscopic submucosal dissection: a scoping review of preclinical and early clinical evidence.

Surgical endoscopy·2026
Same journal

Conversion of endoscopic sleeve gastroplasty to bariatric surgery.

Surgical endoscopy·2026
Same journal

Artificial intelligence and chatbots in general surgery: a survey among surgeons in Germany, Austria and Switzerland.

Surgical endoscopy·2026
See all related articles

Minimally invasive video-assisted thyroidectomy (MIVAT) reduces postoperative pain compared to standard open surgery. This is objectively shown by lower pain scores and specific biochemical markers immediately after the procedure.

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Pain Management

Background:

  • Minimally invasive video-assisted thyroidectomy (MIVAT) is a surgical technique for thyroid removal.
  • Postoperative pain is a significant concern following standard thyroidectomy.
  • Objective assessment of pain using biochemical mediators is crucial.

Purpose of the Study:

  • To objectively compare postoperative pain between MIVAT and standard open thyroidectomy.
  • To investigate the role of biochemical mediators in pain following thyroidectomy.

Main Methods:

  • A prospective, randomized study involving 49 patients undergoing total thyroidectomy.
  • Patients were divided into MIVAT (n=23) and open thyroidectomy (OPEN, n=26) groups.
  • Interleukin (IL) levels, tumor necrosis factor (TNF)-α, TGF-β, MCP-1, and Visual Analog Scale (VAS) pain scores were measured at baseline (T0), in the recovery room (T1), and 24 hours post-surgery (T2).

More Related Videos

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

Related Experiment Videos

Last Updated: Jun 15, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery
05:39

Non-Intubated Video-Assisted Thoracoscopic Surgery

Published on: May 26, 2023

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

Main Results:

  • No significant differences in baseline pain tolerance or biochemical profiles between groups.
  • At T1, the OPEN group had significantly higher VAS scores and lower TGF-β and MCP-1 levels compared to the MIVAT group.
  • TGF-β showed a significant inverse correlation with VAS scores, identified as the most predictive factor for postoperative pain.

Conclusions:

  • TGF-β serum levels immediately post-surgery correlate with pain, suggesting MIVAT reduces postoperative distress objectively.
  • This finding supports subjective pain evaluations and highlights MIVAT's benefits in pain management.