Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 15, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

Development of a pulsatile flow-generating circulatory-assist device.

Syuji Inamori¹, Yutaka Fujii, Tomoya Oshita

¹Department of Clinical Engineering, Faculty of Health Sciences, Hiroshima International University, Hiroshima, Japan.

Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs

|March 3, 2010

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Investigating the structural responses of medial collagen and elastin to traction to elucidate mechanical property differences in porcine aorta and pulmonary artery.

Acta biomaterialia·2026

Same author

Computed tomography-based prediction of commissural positions facilitates valve-sparing aortic root replacement.

JTCVS techniques·2026

Same author

Phase Variance Analysis for Identifying Heterogeneous Conduction Regions in Persistent Atrial Fibrillation: Impact of Recording Duration.

Journal of arrhythmia·2025

Same author

Validation of an intraoperative plantar pressure system in anesthetized patients.

Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons·2025

Same author

Calculated Excess-Triglyceride Based on the Friedewald Formula is a Possible Surrogate Marker for the Production of Large Very-Low Density Lipoprotein, A Post-Hoc Analysis of the PROUD48 Study.

Journal of atherosclerosis and thrombosis·2025

Same author

Association between baseline white blood cell count and future cardiovascular events in patients with stable coronary artery disease- Sub-analysis of the REAL-CAD trial.

American journal of preventive cardiology·2025

Researchers created a novel circulation-assist device that synchronizes pulsatile flow with the patient's diastolic phase. This innovative heart failure treatment showed significant diastolic augmentation in preliminary animal tests.

Area of Science:

Biomedical Engineering
Cardiovascular Research
Medical Devices

Background:

Severe heart failure necessitates advanced circulatory support.
Current methods like percutaneous cardiopulmonary support (PCPS) have limitations.

Purpose of the Study:

To develop and evaluate a novel circulation-assist device.
To achieve pulsatile assist flow synchronized with the patient's diastolic phase.

Main Methods:

Device construction: drainage tube, centrifugal pump, oxygenator, sending tube with a magnetic valve pulse generator.
Preliminary animal experiments conducted over 48 hours.
Assessment of hemodynamics and device functionality.

Main Results:

More Related Videos

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

Published on: October 17, 2013

Related Experiment Videos

Last Updated: Jun 15, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

Published on: October 17, 2013

No adverse hemodynamic changes observed in animal subjects.

No device-related problems reported during the 48-hour test.

Confirmed significant diastolic augmentation.

Conclusions:

The developed device demonstrates potential for treating severe heart failure.
This device may offer advantages over traditional percutaneous cardiopulmonary support (PCPS) alone.