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Related Concept Videos

Introduction to the Integumentary System01:25

Introduction to the Integumentary System

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The integumentary system is the organ system that comprises the skin and its associated structures. It is the largest system in the human body and plays a crucial role in protecting and maintaining homeostasis. The integumentary system serves several functions including protection, regulation, sensation, and secretion.
The skin, which is the primary organ of the integumentary system, consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous tissue). The epidermis is the...
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Papillary Dermis01:11

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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Changes in Skin Color: Clinical Perspectives01:14

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Skin Diseases and Disorders01:23

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Reticular Dermis01:15

Reticular Dermis

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis
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[Dermatology].

Daniel Hohl1

  • 1Service de dermatologie et vénéréologie, CHUV, 1011 Lausanne. Daniel.Hohl@chuv.ch

Revue Medicale Suisse
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PubMed
Summary
This summary is machine-generated.

2009 saw major dermatology advances in infectious diseases, inflammatory disorders, and oncology. Molecular medicine, bioinformatics, and biotechnology are transforming clinical practice, especially in infectious diseases.

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Area of Science:

  • Dermatology
  • Molecular Medicine
  • Bioinformatics
  • Biotechnology

Context:

  • Significant advances in dermatology reported in 2009.
  • Focus areas include infectious diseases, inflammatory disorders, and oncology.
  • The human genome project influences molecular medicine's role in dermatology.

Purpose:

  • To review key 2009 dermatology advancements.
  • To highlight the impact of molecular medicine, bioinformatics, and biotechnology.
  • To note paradigm shifts in infectious disease dermatology.

Summary:

  • Key 2009 dermatology publications covered infectious diseases, inflammatory disorders, and oncology.
  • Molecular medicine, driven by the human genome project, is reshaping dermatology.
  • Bioinformatics and biotechnology are revolutionizing clinical dermatology, particularly in infectious diseases.

Impact:

  • Molecular medicine, bioinformatics, and biotechnology are transforming dermatological practice.
  • A significant paradigm shift is occurring in the field of infectious diseases within dermatology.
  • Enhanced understanding and treatment of dermatological conditions are anticipated.