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Updated: Jun 15, 2026

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Published on: June 20, 2014
Gold(I)-catalyzed tandem cyclization approach to tetracyclic indolines
Yongxiang Liu1, Wenqing Xu, Xiang Wang
1Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309, USA.
Abstract:
Two highly stereoselective cationic gold(I)-catalyzed tandem cyclization reactions of alkynylindoles are described. These reactions demonstrated a novel and general strategy to rapidly construct highly functionalized polycyclic indolines. This approach was successfully employed for a formal synthesis of the akuammiline alkaloid minfiensine.
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