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Related Concept Videos

Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...

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Related Experiment Video

Updated: Jun 15, 2026

Point-of-Care Lung Ultrasound in Adults: Image Acquisition
09:17

Point-of-Care Lung Ultrasound in Adults: Image Acquisition

Published on: March 3, 2023

Pulmonary pseudoneoplasms.

Eunhee Yi1, Marie-Christine Aubry

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.

Archives of Pathology & Laboratory Medicine
|March 4, 2010
PubMed
Summary
This summary is machine-generated.

Surgical pathologists should consider thoracic pseudoneoplasms, which mimic cancer but are benign, when malignancy is not found in excised tissue. Recognizing these nonneoplastic mimics is crucial for accurate diagnosis.

Related Experiment Videos

Last Updated: Jun 15, 2026

Point-of-Care Lung Ultrasound in Adults: Image Acquisition
09:17

Point-of-Care Lung Ultrasound in Adults: Image Acquisition

Published on: March 3, 2023

Area of Science:

  • Pathology
  • Thoracic Surgery
  • Oncology

Background:

  • Surgical pathology often encounters cases with a clinical diagnosis of cancer where no malignancy is identified.
  • Sampling error is a common reason, but nonneoplastic processes (pseudoneoplasms) can also mimic cancer clinically.
  • These pseudoneoplasms can affect the lung, pleura, and mediastinum.

Purpose of the Study:

  • To review common pseudoneoplasms in the thoracic cavity encountered in surgical pathology.
  • To discuss the differential diagnosis of these nonneoplastic conditions.

Main Methods:

  • Literature review and personal case review.
  • Focus on specific entities: inflammatory pseudotumors of the lung, organizing pneumonia, nodular lymphoid hyperplasia, apical cap, round atelectasis, sclerosing mediastinitis, and hyalinizing granuloma.

Main Results:

  • Identified several nonneoplastic conditions that can be mistaken for malignancy in thoracic specimens.
  • Highlighted the importance of recognizing these mimics to avoid misdiagnosis.

Conclusions:

  • When specimens are nondiagnostic for malignancy, consider thoracic pseudoneoplasms.
  • These benign conditions can explain clinical and radiologic findings suggestive of cancer.