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Published on: January 19, 2024
Pediatric iron preparations for infants in Bahrain: some therapeutic concerns
K A J Al Khaja1, R P Sequeira, T Al-Ansari
1Department of Pharmacology and Therapeutics, Arabian Gulf University, Kingdom of Bahrain. khlidj@agu.edu.bh
Insights
Pediatric iron prescribing errors are common in Bahrain, with issues like unavailable brands and incorrect dosages. Improving communication between prescribers and pharmacists is crucial to reduce these medication errors.
Area of Science:
- Pediatric pharmacology
- Medication safety
- Public health
Background:
- Infants and children are particularly vulnerable to medication errors.
- Prescribing errors in pediatric care can have serious consequences.
Purpose of the Study:
- To identify the types and frequency of prescribing errors for pediatric iron preparations in Bahrain's primary care.
- To analyze prescribing patterns of iron supplements for infants.
Main Methods:
- Retrospective audit of 2,282 infant prescriptions from 20 primary care pharmacies.
- Analysis focused on errors in iron preparation prescriptions over a two-week period.
Main Results:
- 7.0% of prescriptions included iron; 90.6% used brand names, many not on the primary care drug list or in pediatric forms.
- Significant prescribing errors included missing dosage forms (26.4%), duration (8.8%), and dosage (2.5%).
- Dosage was often in metric volume (ml), and elemental iron prescribed varied significantly between physicians and nurses.
Conclusions:
- Common errors include using unavailable brands, inconvenient dosage units, and omissions, likely due to poor prescriber-pharmacy communication and lack of information.
- Strengthening communication, discouraging multiple brand procurement, and improving drug supply management are recommended.
- Effective policies are needed to minimize prescribing errors in pediatric iron supplementation in Bahrain.
Background:
Infants and children are at a high risk for medication errors.
Objectives:
This retrospective study was conducted to determine the type and prevalence of prescribing errors related to pediatric iron preparations prescribed in primary care in Bahrain.
Methods:
Prescriptions issued for infants and collected at 20 health center pharmacies for 2 weeks were audited, specifically for errors.
Results:
Of 2,282 prescriptions dispensed for infants (mean age 9.14 +/- 0.91 months), 159 (7.0%) included an iron preparation. Iron preparations were mostly prescribed (90.6%) with brand names, several of which were neither listed in the primary care drug list nor were available as pediatric dosage forms. 42 (26.4%) prescriptions were issued without specifying the dosage forms, 14 (8.8%) without the duration of therapy and 4 (2.5%) without dosage. Iron dosage was stated as metric volume (ml) and metric weight (mg elemental iron) units in 78.6% and 9.4% of the prescriptions, respectively. The mean elemental iron (+/- SD) prescribed for treating anemia was 4.5 +/- 1.7 mg/kg body weight. A significant difference was observed between physicians and nurses regarding the amount of elemental iron prescribed for treating anemia.
Conclusions:
Prescribing of multiple brands of pediatric iron preparations unavailable in the primary care drug list and in pediatric dosage forms, prescribing iron as inconvenient decimal fractions (metric volume units), and omission errors in prescriptions, were common. This may be related to poor communications between the prescribers and the pharmacy services and a lack of information dissemination on newly introduced iron formulations. Moreover, frequent changes in brand availability in primary care may have created confusion for prescribers. The communication between pharmacy services and prescribers should be strengthened, and the procurement of multiple brands should be discouraged. A better management of drug supply and effective policies to minimize prescribing errors are needed in Bahrain.
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