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Related Experiment Video

Updated: Jun 15, 2026

Chick Heart Invasion Assay for Testing the Invasiveness of Cancer Cells and the Activity of Potentially Anti-invasive Compounds
10:16

Chick Heart Invasion Assay for Testing the Invasiveness of Cancer Cells and the Activity of Potentially Anti-invasive Compounds

Published on: June 6, 2015

InPACdb--Indian plant anticancer compounds database.

Umashankar Vetrivel1, Nandhitha Subramanian, Kalabharath Pilla

  • 1School of Biosciences, Department of Bioinformatics, SRM University, Ramapuram Campus, Chennai, India. vumashankar@gmail.com

Bioinformation
|March 4, 2010
PubMed
Summary

The Indian Plant Anticancer Compounds Database (InPACdb) offers phytochemical data for cancer research. It provides comprehensive details on plant-derived compounds, aiding in the discovery of novel anticancer agents.

Keywords:
Biological databaseIndian plantsanticancer compounds

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Chick Heart Invasion Assay for Testing the Invasiveness of Cancer Cells and the Activity of Potentially Anti-invasive Compounds
10:16

Chick Heart Invasion Assay for Testing the Invasiveness of Cancer Cells and the Activity of Potentially Anti-invasive Compounds

Published on: June 6, 2015

Area of Science:

  • Phytochemistry
  • Cheminformatics
  • Pharmacology

Background:

  • Traditional Indian medicine utilizes numerous plant-derived compounds.
  • The anticancer potential of these phytochemicals requires systematic investigation.
  • Existing databases lack comprehensive, integrated data on Indian anticancer phytochemicals.

Purpose of the Study:

  • To establish a centralized, open-access database of anticancer phytochemicals from the Indian pharmacopoeia.
  • To facilitate cheminformatics analysis and drug discovery efforts.
  • To highlight the therapeutic potential of plant-derived compounds in cancer treatment.

Main Methods:

  • Development of a web-based platform, the Indian Plant Anticancer Compounds Database (InPACdb).
  • Compilation of data including cancer type, molecular targets, and 3D stereochemical structures.
  • Inclusion of chemical descriptors and 32 descriptive fields for each phytochemical entry.

Main Results:

  • InPACdb provides a unique, integrated resource for anticancer phytochemicals.
  • The database includes detailed information on stereoisomers, conformers, and resonance structures.
  • Comprehensive data enables effective cheminformatics analysis for drug discovery.

Conclusions:

  • InPACdb serves as a valuable resource for researchers investigating plant-based anticancer agents.
  • The database promotes the exploration of Indian pharmacopoeia for novel cancer therapies.
  • Accessible data supports advancements in phytochemistry and anticancer drug development.