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Updated: Jun 15, 2026

An Integrated Approach for Microprotein Identification and Sequence Analysis
Published on: July 12, 2022
HNHDb: a database on pattern based classification of HNH domains reveals functional relevance of sequence patterns
Alaguraj Veluchamy1, Sujitha Mary, Vishal Acharya
1Center of Excellence in Bioinformatics, School of biotechnology, Madurai Kamaraj University, Madurai, India. alaguraj@mkustrbioinfo.in
Abstract:
The HNH Database is a collection and sequence-based classification of HNH domain proteins. The database contains about 1913 HNH domain containing proteins, and is classified into 10 subsets based on the sequence pattern. Each of these subsets has unique signature sequences. We have shown a correlation between the subset combination and their domain association and function. Functional divergence of this domain may be due to the combination of these conserved patterns and the large variations in the non-conserved regions. HNHDb is freely available at http://bicmku.in:8081/hnh.
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