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Formulating and Characterizing Lipid Nanoparticles for Gene Delivery using a Microfluidic Mixing Platform
Published on: February 25, 2021
A small library of DNA-encapsulated supramolecular nanoparticles for targeted gene delivery
Hao Wang1, Kuan-Ju Chen, Shutao Wang
1Department of Molecular and Medical Pharmacology, Crump Institute for Molecular Imaging (CIMI), University of California, Los Angeles, 570 Westwood Plazas, CNSI Building, Los Angeles, CA 90095-1770, USA. haowang@mednet.ucla.edu
Abstract:
We demonstrated a convenient, flexible and modular synthetic approach for preparation of a small library of DNA-encapsulated supramolecular nanoparticles SNPs superset DNA and RGD-SNPs superset DNA with different sizes and RGD target ligand coverage for targeted gene delivery.
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