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Related Experiment Video

Updated: Jun 15, 2026

Isolation and Culture of Rodent Microglia to Promote a Dynamic Ramified Morphology in Serum-free Medium
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Isolation and Culture of Rodent Microglia to Promote a Dynamic Ramified Morphology in Serum-free Medium

Published on: March 9, 2018

Current concepts of polymicrogyria.

A James Barkovich1

  • 1Neuroradiology, University of California at San Francisco, San Francisco, CA 94143-0628, USA. Jim.Barkovich@radiology.ucsf.edu

Neuroradiology
|March 4, 2010
PubMed
Summary
This summary is machine-generated.

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Polymicrogyria, a common brain malformation, presents diverse appearances on MRI. This review explores the varied clinical and imaging features, indicating greater heterogeneity than previously understood.

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Radiology

Background:

  • Polymicrogyria is a prevalent malformation of cortical development.
  • Its clinical and magnetic resonance imaging (MRI) features are established.
  • Recent imaging studies suggest increased heterogeneity.

Purpose of the Study:

  • To review the diverse appearances of polymicrogyria on MRI.
  • To explore the clinical heterogeneity associated with polymicrogyria.
  • To discuss the implications of polymicrogyria's heterogeneity.

Main Methods:

  • Review of recent literature on polymicrogyria.
  • Analysis of imaging findings from various polymicrogyria cases.
  • Correlation of imaging findings with clinical presentations.

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Last Updated: Jun 15, 2026

Isolation and Culture of Rodent Microglia to Promote a Dynamic Ramified Morphology in Serum-free Medium
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Main Results:

  • Polymicrogyria exhibits a wide spectrum of appearances on MRI.
  • Significant variability exists in clinical manifestations.
  • Imaging findings suggest a more heterogeneous condition than previously thought.

Conclusions:

  • Polymicrogyria is a more heterogeneous malformation than recognized.
  • Diverse MRI appearances reflect underlying heterogeneity.
  • Further research is needed to understand the clinical and imaging spectrum.